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PROTEIN INFORMATIONS


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UniProt logo

The mission of UniProt is to provide the scientific community with a comprehensive, high quality and freely accessible resource of protein sequence and functional information. The site provides UniProtKB (protein knowledgebase) consisting of Swiss-Prot and TrEMBL sections; UniRef that speeds up sequence similarities search; and UniParc a squence archive.

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ExPASy Proteomics Server logo

ExPASy is the Swiss Institute of Bioinformatics (SIB)Bioinformatics Resource Portal which provides access to scientific databases and software tools (i.e., resources) in different areas of life sciences including proteomics, genomics, phylogeny, systems biology, population genetics, transcriptomics etc. (see Categories in the left menu). On this portal you find resources from many different SIB groups as well as external institutions.

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Human Protein Atlas logo
expression and localization of proteins in human tissues

The human protein atlas shows expression and localization of proteins in a large variety of normal human tissues, cancer cells and cell lines with the aid of immunohistochemistry (IHC) images and immunofluorescence (IF) confocal microscopy images (Marx V., Nature 509:645, 2014).

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DIP: Interacting Proteins DB logo

The DIP database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions.

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Proteome Tools logo

The ProteomeTools project is a joint effort of the Technical University of Munich (TUM), JPT Peptide Technologies, SAP SE and Thermo Fisher Scientific. It is dedicated to translating the human proteome into molecular and digital tools for drug discovery, personalized medicine and life science research. Over the course of the project, ~1.4 million synthetic peptides covering essentially all human gene products including important post translational modifications will be synthesized and analyzed u

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Binding DB logo

BindingDB is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of protein considered to be drug-targets with small, drug-like molecules.

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STITCH logo
Subcategories: EMBL

STITCH is a resource to explore known and predicted interactions of chemicals and proteins. Chemicals are linked to other chemicals and proteins by evidence derived from experiments, databases and the literature.

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PANTHER: Classification System logo
Geneontology

The PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System is a unique resource that classifies genes by their functions, using published scientific experimental evidence and evolutionary relationships to predict function even in the absence of direct experimental evidence.

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MAPU logo

MAPU is the Max-Planck Unified Proteome DB. Mass spectrometry (MS)-based proteomics on body fluids, cell lines, red blood cells, liver. MAPU datasets can serve as reference proteomes in biomarker discovery.

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NCBI protein logo
Subcategories: ncbi

The Protein database is a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. Protein sequences are the fundamental determinants of biological structure and function.

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EBI logo
EMBL European Bioinformatic Istitute
Subcategories: EMBL

EBI (EMBL European Bioinformatic Istitute) home page provides a central access point to search several databases for information on genes, proteins, enzymes etc.

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PDBsum: Protein 3D dabase logo
Subcategories: EMBL

PDBsum provides an at-a-glance overview of every macromolecular structure deposited in the Protein Data Bank (PDB), giving schematic diagrams of the molecules in each structure and of the interactions between them.

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PhosphoSitePlus logo

PhosphoSitePlus® (PSP) is an online systems biology resource providing comprehensive information and tools for the study of protein post-translational modifications (PTMs). In addition to providing an extensive, manually curated phosphorylation site database, other commonly studied PTMs are included in PSP.

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Enzyme Info Brenda logo

The Comprehensive Enzyme Information System

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GelBank logo
Protein gel image repository

GelBank is a public archive for gel images annotated or prepared by GelScape (or any software tool that generates image-mapped gel images). It is a fully searchable web-enabled gel image databank which adheres to the general guidelines suggested for federated gel databases

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PDB Protein Data Bank logo

The Worldwide Protein Data Bank (wwPDB) consists of organizations that act as deposition, data processing and distribution centers for PDB data. The founding members are RCSB PDB (USA), PDBe (Europe) and PDBj (Japan) whic act as data deposition, processing and distribution centers for PDB data (RP Josten et al, Nucleic Acid Res 39, D411, 2011).

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MEROPS logo
Peptidase Database
Subcategories: EMBL

The MEROPS database is an information resource for peptidases (also termed proteases, proteinases and proteolytic enzymes) and the proteins that inhibit them.

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Peptide Atlas logo

PeptideAtlas is a multi-organism, publicly accessible compendium of peptides identified in a large set of tandem mass spectrometry proteomics experiments. Mass spectrometer output files are collected for human, mouse, yeast, and several other organisms, and searched using the latest search engines and protein sequences.

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Proteome Commons logo

Proteome Commons is a public proteomics database for annotations and other information linked to the Tranche data repository and to other resources. The site is a project management tool that functions like some social networking websites. Users register, sign into the system, create a new project, and then invite colleagues and collaborators to the project. Invitees are given permissions and responsibilities by the project’s creator.

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ChEMBL protein-ligand interaction logo
Subcategories: EMBL

ChEMBL, an open-access database, contains more than 5 million interactions between proteins and ligands that have been published in peer-reviewed journals or reported by laboratories and screening centers . Under ChEMBL’s “Ligand Search” tab, you can enter a compound’s SMILES notation in the “List Search” box and click “Fetch Compounds.” On the next page, clicking on the ChEMBL compound identifier under the 2-D drawing takes you to the Compound Report Card page, which includes th

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