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DIP: Interacting Proteins DB logo

The DIP database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions.

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known and predicted protein interactions

STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations. They are derived from Genomic Context, High-throughput Experiments (Conserved), Coexpression, Previous Knowledge. STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable. The database currently covers 2,590,259 proteins from 630 organ

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DIMA logo
domain interaction map

DIMA (Domain Interaction MAp) aims at becoming a comprehensive resource for functional and physical interactions among conserved protein-domains. The scope of the resource comprises both experimental data and computational predictions (Q Luo et al., Nucleic Acid Res 39, D724, 2011)

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Binding DB logo

BindingDB is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of protein considered to be drug-targets with small, drug-like molecules.

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I2D logo
known and predicted protein interaction search

I2D (Interologous Interaction Database) is a web application designed to explore known and predicted protein-protein interactions and to facilitate bioinformatics initiatives exploring protein interaction networks.

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MiMI logo

MiMi (Molecular interactions) Web gives you an easy to use interface to a rich NCIBI data repository for conducting your systems biology analyses.In particular, MiMI provides access to the knowledge and data merged and integrated from numerous protein interactions databases

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a database of known and predicted protein domain-domain interactions

DOMINE is a database of known and predicted protein domain (domain-domain) interactions (S Yellaboina, Nucleic Acid Res 39, D730, 2011).

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Subcategories: EMBL

STITCH is a resource to explore known and predicted interactions of chemicals and proteins. Chemicals are linked to other chemicals and proteins by evidence derived from experiments, databases and the literature.

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MINT logo
protein-protein interactions mined from the scientific literature

The Molecular INTeraction database (MINT) focuses on experimentally verified protein-protein interactions mined from the scientific literature by expert curators. The full MINT dataset can be freely downloaded.

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BioGRID logo

The Biological General Repository for Interaction Datasets (BioGRID) is a public database that archives and disseminates genetic and protein interaction data from model organisms and humans

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