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sTRAP (Transcription factor Affinity Prediction) is a web application to calculate how the binding of different TFs is affected by the sequence differences (e.g. by single-nucleotide polymorphism) Registration not required.
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It's a simple and well constructed Excel spreadsheet from Jon Wittwer of Vertex42 for graphing a Normal distribution curve by inputing either a mean & SD or single subject values. In addition the spreadsheet includes examples for generating a random number from a Normal distribution, for calculating cumulative probabilities and for shading a portion of the distribution. Registration not required.
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This page computes various statistics from a 2-by-2 table. It will calculate the Yates-corrected chi-square, the Mantel-Haenszel chi-square, the Fisher Exact Test, and other indices relevant to various special kinds of 2-by-2 tables. Registration not required.
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Ensembl, a genome browser project, produces genome databases for vertebrates, and makes this information freely available online. Registration not required.
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Buffer solutions for pH control Registration not required.
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The Gene Expression Omnibus (GEO - NCBI) is a public repository archiving and freely distributing microarray, next-generation sequencing, and other forms of high-throughput functional genomic data submitted by the scientific community. In addition to data storage, a collection of web-based interfaces and applications are available to help users query and download the experiments and gene expression patterns stored in GEO. Registration not required.
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The mission of UniProt is to provide the scientific community with a comprehensive, high quality and freely accessible resource of protein sequence and functional information. The site provides UniProtKB (protein knowledgebase) consisting of Swiss-Prot and TrEMBL sections; UniRef that speeds up sequence similarities search; and UniParc a squence archive. Registration not required.
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QuantPrime is very user-friendly tool for primer pair design in small- to large-scale real-time reverse transcription qPCR analyses. It offers design and specificity checking with highly customizable parameters and is ready to use with most publicly available eukaryotic transcriptomes, including all higher eukaryote model organisms and important plant crops, while benefiting from exon-intron border and splice variant information in available genome annotations. Registration not required.
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Use this calculator to compute a P value from a Z, t, F, r, or chi-square value. Registration not required.
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PepNovo is a high throughput de novo peptide sequencing tool for tandem mass spectrometry data. PepNovo typically runs in less than 0.2 seconds per spectrum. PepNovo uses a probabilistic network to model the peptide fragmentation events in a mass spectrometer. Registration not required.
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A very intuitive tool to design primer. The request need the entering of gene sequence or sequence of interest (multiple sequences in FASTA format with exons in uppercase letters and introns in lowercase letters, positive orientation). A complete tutorial is available. Registration not required.
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GeneFisher2 is a very good site allowing great control over primer design Registration not required.
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Compare two sequences aligns two sequences using the indicated algorithm, and calculates the statistical significance using shuffled sequences. Registration not required.
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Category: Calculators and converters
Expasy Translate allows: translate a nucleotide (DNA/RNA) sequence to a protein sequence
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