Cancer Genome Project has embarked on a systematic characterisation of the genetics and genomics of large numbers of cancer cell lines. Prior knowledge of their genetic abnormalities may allow more informed choice of cancer cell lines in biological experiments and drug testing and more informed interpretation of results.
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The non-profit ATCC (American Type Culture Collection) Cell Products is the most comprehensive and diverse of its kind in the world, consisting of over 3,600 cell lines from over 150 different species. It holds over 950 cancer cell lines, 1,000 hybridomas and several special collections including stem cells.
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DSMZ is the German Resource Center for Human, Animal Cell and microorganisms Culture Collection. The DSMZ currently hosts more than 79,000 bioresources, most of them are available from online catalogues.
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The Broad-Novartis Cancer Cell Line Encyclopedia (CCLE) is an ongoing project from collaboration between the Broad Institute, and the Novartis Institutes for Biomedical Research and its Genomics Institute of the Novartis Research Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models, to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative
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The Cell Line Integrated Molecular Authentication (CLIMA) database is the result of an integration effort aimed at including all certified STR profiles of human cell lines in a unique database. Its main feature is cell line identification according to the standard ANSI/ATCC ASN-0002-2011, but it also provides features for searching profiles by cell line name and by locus.
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The European Collection of Authenticated Cell Cultures (ECACC) is one of four Culture Collections of the UK Health Security Agency. We supply authenticated and quality controlled cell lines, nucleic acids and induced Pluripotent Stem Cells (iPSCs).
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The International Cell Line Authentication Committee aims to make false or misidentified cell lines more visible, and promote awareness and authentication testing as effective ways to combat the problem. It provides a database listing cell lines that are currently known to be cross-contaminated or misidentified.
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The FCS-free Database (RRID:SCR_018769), part of the 3Rs Database Programme, provides an overview of FCS-free media for cell-culture. A forum function for each record allows researchers to discuss the applicability of each product. The database is offered by the 3Rs-Centre ULS in collaboration with Animal Free Research UK.
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