The Connectivity Map uses computer algorithms and genome-wide expression data to explore the connection between diseases, genes, and drugs. Cmap is a collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules and simple pattern-matching algorithms that together enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes. The aim of theConnectivity Map project is to provide a systematic solution for the discovery of the type of functional connections between drugs, genes and diseases. Registration required.