The TRIP Database is a clinical search engine designed to allow clinicians to quickly find answers to their clinical questions using the best available evidence. The creation of the TRIP Database allowed the simultaneous searching of multiple sites, hence speeding up the question answering process. The evolution of the TRIP Database has been guided by the desire to answer real clinical questions using the principles of evidence based medicine. TRIP Database Ltd’s involvement in clinical question answering has shown the type of material that is useful in answering genuine questions health professionals have. Registration not required.