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Cancer Cell Line Encyclopedia logo
Cancer Cell Line Encyclopedia
Category: Cell lines
Subcategories: Broad

The Broad-Novartis Cancer Cell Line Encyclopedia (CCLE) is an ongoing project from collaboration between the Broad Institute, and the Novartis Institutes for Biomedical Research and its Genomics Institute of the Novartis Research Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models, to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative ... Registration required.

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HaploReg logo
HaploReg
Category: Genetic variations
Subcategories: Broad

HaploReg is a tool for exploring annotations of the noncoding genome at variants on haplotype blocks, such as candidate regulatory SNPs at disease-associated loci. It brings together data from chromatin-mapping and comparative-genomics studies. Researchers can enter common variants and see whether they fall in a highly conserved region, disrupt a regulatory motif or are associated with a regulatory element in a particular cell type. It provides the same information for common variants that tend ... Registration not required.

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Connectivity map (cmap) logo
Connectivity map (cmap)
Category: Cancer research, Other topics
Subcategories: Broad

The Connectivity Map uses computer algorithms and genome-wide expression data to explore the connection between diseases, genes, and drugs. Cmap is a collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules and simple pattern-matching algorithms that together enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes. The aim of theConnectivity ... Registration required.

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Argo Genome Browser logo
Argo Genome Browser
Category: Genomics software
Subcategories: Broad

The Argo Genome Browser is the Broad Institute's production tool for visualizing and manually annotating whole genomes. It's a free and open source standalone Java 1.4 application. Registration not required.

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TumorPortal logo
TumorPortal
Category: Cancer research
Subcategories: Broad

TumorPortal, developed and maintained by the Broad Institute of Harvard and MIT, hosts a ‘pan-cancer’ data set from several tumor types. It provides visualization of computationally processed gene information. It shows which genes are mutated in many tumor samples and types. Registration not required.

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