NOVELTIES
Compute pI/Mw is a tool which allows the computation of the theoretical pI (isoelectric point) and Mw (molecular weight) for a list of Swiss-Prot entries or for a user entered sequence of aminoacids. The resulting theoretical values check the consistency of the position on a 2D PAGE gel of the identified and unmodified proteins. Registration not required.
Click here for more informationsPublished on 2011-05-04 04:43:58
STITCH is a resource to explore known and predicted interactions of chemicals and proteins. Chemicals are linked to other chemicals and proteins by evidence derived from experiments, databases and the literature. Registration not required.
Click here for more informationsPublished on 2011-05-03 12:21:46
Proteomics tools for mining sequence databases in conjunction with mass spectrometry experiments. Registration not required.
Click here for more informationsPublished on 2011-05-03 12:09:00
X!Tandem is a very fast seach engine which searches for matches of MS/MS spectra to a protein database. X!Tandem is free to use on the web or to download. X!Tandem works in conjunction with thegpm.org and can take advantage of the information gleaned from previous searches. It has an option, PPP, which searches first only the peptides that have been found most frequently for each protein Registration not required.
Click here for more informationsPublished on 2011-05-03 12:07:36
The standard MS/MS experiment starts by digesting the proteins into peptides with an enzyme such as trypsin. USe Protein Digestor to see what peptides will result from digesting a protein. Registration not required.
Click here for more informationsPublished on 2011-05-03 12:06:51
PepNovo is a high throughput de novo peptide sequencing tool for tandem mass spectrometry data. PepNovo typically runs in less than 0.2 seconds per spectrum. PepNovo uses a probabilistic network to model the peptide fragmentation events in a mass spectrometer. Registration not required.
Click here for more informationsPublished on 2011-05-03 11:33:41
The database of Genotypes and Phenotypes (dbGaP) was developed to archive and distribute the results of studies that have investigated the interaction of genotype and phenotype. Such studies include genome-wide association studies, medical sequencing, molecular diagnostic assays, as well as association between genotype and non-clinical traits. Registration not required.
Click here for more informationsPublished on 2011-05-03 09:49:50
Health on the Net Foundation (HON): Search only reliable and trustworthy medical websites Registration not required.
Click here for more informationsPublished on 2011-05-03 09:49:14
Browse the Web's Largest Acronyms & Abbreviations Resource Registration not required.
Click here for more informationsPublished on 2011-05-03 09:40:57
Pathway Commons is a convenient point of access to biological pathway information collected from public pathway databases (EG Cerami et al., Nucleic Acid Res 39, D685, 2011) Registration not required.
Click here for more informationsPublished on 2011-05-02 09:50:26
PubChem (NCBI) provides information on the biological activities of small molecules. It is a component of NIH's Molecular Libraries Roadmap Initiative. PubChem includes substance information, compound structures, and BioActivity data in three primary databases, Pcsubstance, Pccompound, and PCBioAssay, respectively. The Substance/Compound database, where possible, provides links to BioAssay description, literature, references, and assay data points. The BioAssay database also includes links back to the Substance/Compound database. PubChem is integrated with Entrez, NCBI's primary search engine, and also provides compound neighboring, sub/superstructure, similarity structure, BioActivity data, and other searching features. PubChem contains substance and BioAssay information from a multitude of depositors. Registration not required.
Click here for more informationsPublished on 2011-05-02 07:43:15
eMolecules is a chemical structure search engine that links also to suppliers. The standard search allows querying for names, substructures, and suppliers. Registration not required.
Click here for more informationsPublished on 2011-05-02 07:42:19
ChemSpider is a free-to-access collection of compound data from across the web, that offers text and structure searching to find compounds of interest and provides unique services to improve this data by curation and annotation and to integrate it with users’ applications. Registration not required.
Click here for more informationsPublished on 2011-05-02 07:40:08
The Common Fund's Genotype-Tissue Expression (GTEx) program aims to map all sites in the human genome where sequence variation quantitatively affects gene expression and regulation in multiple tissues, providing valuable insights into the mechanisms of gene regulation and its disease-related perturbations. Registration not required.
Click here for more informationsPublished on 2011-05-01 14:49:52
The Allen Mouse Brain Atlas is a comprehensive genome-wide map of the adult mouse brain revealing where each gene is expressed, or “turned on. A combination of RNA in situ hybridization data, detailed Reference Atlases and informatics analysis tools are integrated to provide a searchable digital atlas of gene expression. Together, these resources present a comprehensive online platform for exploration of the brain at the cellular and molecular level. Registration not required.
Click here for more informationsPublished on 2011-05-01 14:42:45
The Argo Genome Browser is the Broad Institute's production tool for visualizing and manually annotating whole genomes. It's a free and open source standalone Java 1.4 application. Registration not required.
Click here for more informationsPublished on 2011-05-01 13:41:58
The EST database (NCBI) is a collection of short single-read transcript sequences from GenBank. These sequences provide a resource to evaluate gene expression, find potential variation, and annotate genes. Registration not required.
Click here for more informationsPublished on 2011-05-01 13:36:27
HomoloGene (NCBI) is a system for automated detection of homologs among the annotated genes of several completely sequenced eukaryotic genomes. Registration not required.
Click here for more informationsPublished on 2011-05-01 13:29:26
The DNV database (dbDNV) has been established to promote more accurate variation annotation. Aside from the flat file download, users can explore the gene-related duplications and the associated DNVs by DGL and DNV searches, respectively Registration not required.
Click here for more informationsPublished on 2011-05-01 06:10:55
By extensive analyses of all human transcripts, H-InvDB (Integrated DB of Annotated Human Genes) provides curated annotations of human genes and transcripts that include gene structures, alternative splicing isoforms, non-coding functional RNAs, protein functions, functional domains, sub-cellular localizations, metabolic pathways, protein 3D structure, genetic polymorphisms (SNPs, indels and microsatellite repeats) , relation with diseases, gene expression profiling, and molecular evolutionary features , protein-protein interactions (PPIs) and gene families/groups. Registration not required.
Click here for more informationsPublished on 2011-05-01 05:59:01
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